Diphtheria (Corynebacterium diphtheriae)

Corynebacteria are Gram-positive, aerobic, nonmotile, rod-shaped bacteria related to the Actinomycetes. They do non form spores or branch as do the actinomycetes, evidently they ware the indication of forming irregular shaped, club-shaped or V-shaped arrangements in practice growth. They endure snapping movements just after cell division which brings them into characteristic arrangements resembling Chinese letters. The genus Corynebacteria consists of a respective(a) group of bacteria including animal and kit and boodle pathogens, as surface as saprophytes. Some corynebacteria are activate of the normal flora of public, finding a suitable quoin in virtually every anatomical site. The best cognize and most widely canvas species is Corynebacterium diphtheriae, the causal broker of the unhealthiness diphtheria. History and Background No bacterial disease of humans has been as success plenteousy studied as diphtheria. The etiology, mode of transmission, infectious me chanism and molecular terra firma of exotoxin structure, function, and action have been clearly established. Consequently, extremely effective methods of treatment and prevention of diphtheria have been developed. The study of Corynebacterium diphtheriae traces about the development of medical microbiology, immunology and molecular biology. Many contributions to these fields, as well as to our understanding of host-bacterial interactions, have been made studying diphtheria and the diphtheria toxin. Hippocrates provided the beginning clinical description of diphtheria in the 4th century B.C. there are also references to the disease in ancient Syria and Egypt. In the 17th century, murderous pandemics of diphtheria swept Europe; in Spain El garatillo (the strangler), in Italy and Sicily, the gullet disease. In the 18th century, the disease reached the American colonies and reached epidemic proportions in 1735. Often, whole families died of the disease in a fewer weeks. The b acterium that caused diphtheria was first de! scribed by Klebs in 1883, and was courtly by Loeffler in 1884, who applied Kochs postulates and properly identified Corynebacterium... If you motivation to get a full essay, order it on our website: OrderCustomPaper.com

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